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Detection of ESR1 methylation

Detection of ESR1 methylation using real-time MSP


  • Gene: ESR1
  • Methodology: real-time MSP 
  • Instrumentation: LightCycler 2.0 (IVD, Roche Diagnostics)
  • Analytical characteristics: exceptional analytical sensitivity and specificity
  • Requested sample: 20mL peripheral blood (EDTA) - pre-, during or post-therapy 
  • Cost: please contact Dr E.Lianidou (lianidou@chem.uoa.gr)

 

  • Clinical importance:

Mastoraki S, Strati A, Tzanikou E, Chimonidou M, Politaki H, Voutsina A, Psyrri A, Georgoulias V, Lianidou ES. ESR1 methylation: a liquid biopsy-based epigenetic assay for the follow up of patients with metastatic breast cancer receiving endocrine treatment. Clin Cancer Res 2018 Mar;24:1500-1510